1+ months

Biomedical Scientist - Immunology

Lawrence Livermore National Laboratory
Livermore, CA 94550

We have an opening for a Biomedical Scientist to research for executing experiments to identify and produce proteins for nanoparticle-based vaccine development. You will expect to learn new skills and be able to implement them independently, as part of a multidisciplinary team. We value diverse perspective and strongly encourage applications from historically underrepresented groups. This position is in the Biosciences and Biotechnology Division.

This position will be filled at either the SES.1 or SES.2 level, depending on your qualifications. Additional job duties will be assigned at the higher level.

In this role you will:

  • Conduct in vitro and in vivo protein expression/purification to generate reagents for functional and immunological studies.
  • Prepare biological samples for immunological experiments in cells and/or animals.
  • Evaluate large data sets to troubleshoot assays as needed.
  • Maintain an accurate and detailed laboratory notebook and communicate results with relevant team members.
  • Ensure that all experiments are performed within ES&H safety guidelines and that waste from all experiments is characterized and disposed of properly.
  • Perform other duties as assigned.

Additional duties at the SES.2 Level:

  • Design and validate synthetic DNA constructs for protein expression.
  • Characterize proteins in terms of yield, purity and stability.
  • Design in vitro functional and structural assays to correlate with vaccine safety and efficacy.
  • Evaluate large data sets to refine, inform, and design subsequent experiments.

  • Bachelor's degree in Molecular Biology, or related field, or the equivalent combination of education and related experience.
  • Working knowledge of basic recombinant and microbial techniques, including synthetic gene design, expression optimization and promoter utilization.
  • Ability to understand new concepts quickly, apply them accurately throughout an evolving environment, and gain proficiency to work independently to meet established guidelines.
  • Experience working effectively in a fast-paced, multidisciplinary environment both independently and as a team with a diverse set of scientists, engineers, and other technical and administrative staff.
  • Proficient with common software (e.g., Microsoft Office applications) and able to quickly learn new software.

Additional qualifications at the SES.2 level

  • Master's degree in Molecular Biology, or related field, or the equivalent combination of education and related experience.
  • Experience in protein expression, purification and characterization.
  • Experience characterizing immune responses in cellular and animal models.
  • Comprehensive knowledge and experience in animal handling, various vaccination techniques, and typical molecular biology laboratory instruments.

Qualifications we desire

  • Experience with recombinant DNA technology.
  • Working knowledge of protein purification and characterization techniques and experience with sample preparation and processing.
  • Willingness to work with animal models, and DNA and RNA extraction protocols.
  • Working knowledge of nanoparticle platforms and vaccine formulations and administration.

All your information will be kept confidential according to EEO guidelines.

Position Information

This is a Flexible Term appointment, which is for a definite period not to exceed six years.

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Why Lawrence Livermore National Laboratory?

  • Included in 2022 Best Places to Work by Glassdoor!
  • Work for a premier innovative national Laboratory
  • Comprehensive Benefits Package
  • Flexible schedules (*depending on project needs)
  • Collaborative, creative, inclusive, and fun team environment

Learn more about our company, selection process, position types and security clearances by visiting our Career site.

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COVID-19 Vaccination Mandate

LLNL demonstrates its commitment to public safety by requiring that all new Laboratory employees be immunized against COVID-19 unless granted an accommodation under applicable state or federal law. This requirement will apply to all new hires including those who will be working on site, as well as those who will be teleworking.

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Security Clearance

None required. However, if your assignment is longer than 179 days cumulatively within a calendar year, you must go through the Personal Identity Verification process. This process includes completing an online background investigation form and receiving approval of the background check. (This process does not apply to foreign nationals.) For additional information, please see DOE Order 472.2.

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Pre-Employment Drug Test

External applicant(s) selected for this position will be required to pass a post-offer, pre-employment drug test. This includes testing for use of marijuana as Federal Law applies to us as a Federal Contractor.

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Pre-Placement Medical Exam

A job related pre-placement medical examination may be required.

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Equal Employment Opportunity

LLNL is an affirmative action and equal opportunity employer that values and hires a diverse workforce. All qualified applicants will receive consideration for employment without regard to race, color, religion, marital status, national origin, ancestry, sex, sexual orientation, gender identity, disability, medical condition, pregnancy, protected veteran status, age, citizenship, or any other characteristic protected by applicable laws.

If you need assistance and/or a reasonable accommodation during the application or the recruiting process, please submit a request via our online form.

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California Privacy Notice

The California Consumer Privacy Act (CCPA) grants privacy rights to all California residents. The law also entitles job applicants, employees, and non-employee workers to be notified of what personal information LLNL collects and for what purpose. The Employee Privacy Notice can be accessed here.


Join us and make YOUR mark on the World!

Are you interested in joining some of the brightest talent in the world to strengthen the United States' security? Come join Lawrence Livermore National Laboratory (LLNL) where our employees apply their expertise to create solutions for BIG ideas that make our world a better place.

We are committed to a diverse and equitable workforce with an inclusive culture that values and celebrates the diversity of our people, talents, ideas, experiences, and perspectives. This is essential to innovation and creativity for continued success of the Laboratory's mission.

"},"jobDescription":{"title":"Job Description","text":"

We have an opening for a Biomedical Scientist to research for executing experiments to identify and produce proteins for nanoparticle-based vaccine development. You will expect to learn new skills and be able to implement them independently, as part of a multidisciplinary team. We value diverse perspective and strongly encourage applications from historically underrepresented groups. This position is in the Biosciences and Biotechnology Division.

This position will be filled at either the SES.1 or SES.2 level, depending on your qualifications. Additional job duties will be assigned at the higher level.

In this role you will:

  • Conduct in vitro and in vivo protein expression/purification to generate reagents for functional and immunological studies.
  • Prepare biological samples for immunological experiments in cells and/or animals.
  • Evaluate large data sets to troubleshoot assays as needed.
  • Maintain an accurate and detailed laboratory notebook and communicate results with relevant team members.
  • Ensure that all experiments are performed within ES&H safety guidelines and that waste from all experiments is characterized and disposed of properly.
  • Perform other duties as assigned.

Additional duties at the SES.2 Level:

  • Design and validate synthetic DNA constructs for protein expression.
  • Characterize proteins in terms of yield, purity and stability.
  • Design in vitro functional and structural assays to correlate with vaccine safety and efficacy.
  • Evaluate large data sets to refine, inform, and design subsequent experiments.
"},"qualifications":{"title":"Qualifications","text":"
  • Bachelor's degree in Molecular Biology, or related field, or the equivalent combination of education and related experience.
  • Working knowledge of basic recombinant and microbial techniques, including synthetic gene design, expression optimization and promoter utilization.
  • Ability to understand new concepts quickly, apply them accurately throughout an evolving environment, and gain proficiency to work independently to meet established guidelines.
  • Experience working effectively in a fast-paced, multidisciplinary environment both independently and as a team with a diverse set of scientists, engineers, and other technical and administrative staff.
  • Proficient with common software (e.g., Microsoft Office applications) and able to quickly learn new software.

Additional qualifications at the SES.2 level

  • Master's degree in Molecular Biology, or related field, or the equivalent combination of education and related experience.
  • Experience in protein expression, purification and characterization.
  • Experience characterizing immune responses in cellular and animal models.
  • Comprehensive knowledge and experience in animal handling, various vaccination techniques, and typical molecular biology laboratory instruments.

Qualifications we desire

  • Experience with recombinant DNA technology.
  • Working knowledge of protein purification and characterization techniques and experience with sample preparation and processing.
  • Willingness to work with animal models, and DNA and RNA extraction protocols.
  • Working knowledge of nanoparticle platforms and vaccine formulations and administration.

Categories

Posted: 2022-04-28 Expires: 2022-06-30

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Biomedical Scientist - Immunology

Lawrence Livermore National Laboratory
Livermore, CA 94550

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